Crosslinkable collagen derivatives, process for their production

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.

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106124, 106125, 602 42, 602 43, 602 48, 602 50, 424443, 424444, 424445, 424484, A61K 3712, A61K 970, C07K 1300, A61L 1532

Patent

active

054120764

ABSTRACT:
The present invention relates to a crosslinkable modified collagen which is soluble in water and/or in aprotic polar organic solvents and which contains free or substituted thiol groups carried by residues of cysteine or derivatives thereof, at least some of the residues being fixed to the collagen via spacer compounds. It further relates to processes for the production of the collagen. Applications are adhesives, biomaterials for prostheses, implants, or other medical articles.

REFERENCES:
patent: 4294241 (1981-10-01), Miyata
patent: 4407787 (1983-10-01), Stemberger
patent: 5219895 (1993-06-01), Kelman et al.

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