Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds bacterium or component thereof or substance produced...
Reexamination Certificate
2005-01-11
2005-01-11
Graser, Jennifer E. (Department: 1645)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds bacterium or component thereof or substance produced...
C424S164100, C530S387200, C530S388100, C530S388150, C530S387300, C530S387900, C530S388400
Reexamination Certificate
active
06841154
ABSTRACT:
Polyclonal and monoclonal antibodies which are cross-reactive to both coagulase-positive staphylococcus bacteria, such asS. aureusand to coagulase-negative bacteria, such asS. epidermidisandS. hemolyticus, are provided which can recognize surface proteins from both coagulase-positive and coagulase negative staph bacteria. The antibodies may be generated from surface proteins that have been isolated on the basis of characteristics that may be common betweenS. aureusand coagulase-negative staphylococci, and these recombinant surface proteins are used to generate the antibodies of the invention. There is also provided vaccines and methods which utilize these proteins and antibodies for the treatment or protection against a wide variety of staphylococcal infections.
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Foster Timothy
Hutchins Jeff T.
Pallen Mark
Patti Joseph M.
Roche Fiona
Graser Jennifer E.
Inhibitex, Inc.
Schulman B. Aaron
Stites & Harbison PLLC
The Provost Fellows and Scholars of the College of the Holy and
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