Cross-reactive influenza a immunization

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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Details

4241841, 4242041, 4242051, A61K 3912, A61K 39145, A61K 3900, A61K 3938

Patent

active

056745028

ABSTRACT:
This disclosure relates to methods and compositions for stimulating in an individual an influenza A virus protective response which is subtype cross-protective. Influenza A virus NS1 protein, or a T cell epitope thereof, is administered to the individual in an amount sufficient to stimulate the virus protective response.

REFERENCES:
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Cossins, Judy et al., "Precise Prediction of a K.sup.k -Restricted Cytotoxic T Cell Epitope in the NS1 Protein of Influenza Virus Using an MHC Allele-Specific Motif," Virology, 19 (31):289-295 (1993).
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