Cross-reactive and protective epitopes of CS

Details Cross-reactive and protective epitopes of CS Cross-reactive and protective epitopes of CS

1987-10-26

1990-04-10

Moskowitz, Margaret

Drug, bio-affecting and body treating compositions

Lymphokine

530300, 530350, 530820, 530806, 530325, 530326, 530327, 530825, 514 2, 514 12, 514 13, 514 14, 435 693, 424 858, C07K 700, A61K 3574, A61K 3702

Patent

active

049159429

ABSTRACT:
Synthetic peptides containing non-repeating epitopes of circumsporozoite derived protein antigen and which are substantially shorter in length than the intact antigen are disclosed. The peptides when administered to a host raise antibodies in that host that will bind to the circumsporozoite antigen on the parasite. Vaccines based upon these peptides, as well as means of raising antibodies to circumsporozoite antigens using the synthetic peptides are also disclosed.

REFERENCES:
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