Cross-reactive and protective epitopes of circumsporozoite prote

Details Cross-reactive and protective epitopes of circumsporozoite prote Cross-reactive and protective epitopes of circumsporozoite prote

1989-06-22

1993-01-12

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Lymphokine

530327, 530326, 530325, 514 12, 514 13, H61K 3574, H61K 3702, C07K 700

Patent

active

051788616

ABSTRACT:
Disclosed is a peptide antigen comprising an amino acid sequence of a non-repetitive epitope of the circumsporozoite protein of a sporozoite of the genus plasmodium said peptide having the property of eliciting formation of antibodies that bind to said nonrepetitive epitope on the sporozoite surface said peptide being synthetic, purified and substantially shorter in length than said protein.

REFERENCES:
patent: 4466917 (1984-08-01), Nussenzweig et al.
patent: 4769235 (1988-09-01), Schlesinger et al.
patent: 4915942 (1990-04-01), Vergara et al.

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