Cross-protective fowl cholera bacterins

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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A61K 3902

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active

041361695

ABSTRACT:
Cross-protection of fowl against different serologic and immunologic types of Pasteurella multocida, responsible for fowl cholera, has been achieved by a novel process for preparing P. multocida bacterins. Bacterial cells from infected fowl tissue are passaged only once through a laboratory medium, sterilized, and recovered for use.

REFERENCES:
patent: 2787576 (1957-04-01), Kakavas et al.
patent: 3139382 (1964-06-01), Killinger
patent: 3328252 (1967-06-01), Mora
patent: 3855408 (1974-12-01), Maheswaran
Heddleston Avian Diseases vol. VI, No. 3, pp. 315-321 (1962) Studies on Pasteurellosis. v. Two Immunoganic types of Pasteurella multocida Associated with Fowl Cholera.
Heddleston et al. Avian Diseases vol. IX No. 3, pp. 367-376 (1965) Fowl Chloera; Comparison of Serologic and Immunogenic Responses of Chickens and Turkeys.
Heddleston et al. Avian Diseases vol. 16 No. 3; pp. 578-586 (1972) Fowl Cholera; Cross-Immunity induced in Turkeys with formalin-killed in-vivo Propagated Pasteurella multocida.
Heddleston et al. Avian Diseases vol. 18 No. 2: pp. 213-214 (1974) "Fowl Cholora Bacterins: Host-Specific cross-immunity induced in turkeys with Pasteurella multocida propagated in embryonating turkey eggs".

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