Cross-linking proteins with bimetallic tetracarboxylate compound

Details Cross-linking proteins with bimetallic tetracarboxylate compound Cross-linking proteins with bimetallic tetracarboxylate compound

1989-01-17

1991-03-05

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an organic...

435176, 435181, 530356, 530811, 530812, 530816, C12N 1102, C12N 1106, C07K 1702, C07K 1706

Patent

active

049977580

ABSTRACT:
Stable cross-linked complexes of transition-metal tetracarboxylates and proteins are formed. The preferred transition-metal is rhodium. The protein may be collagen or an enzyme such as a proteolytic enzyme.

REFERENCES:
Zaborsky, O. R., Biomedical Applications of Immobilized Enzymes and Proteins, vol. 1, 1977, pp. 25-35.
Nakatsuji et al., Chemical Abstracts, 98: 20661of, 1983, p. 525

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