Cross-linking collagenous product

Chemistry: electrical and wave energy – Processes and products – Processes of treating materials by wave energy

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530356, C07K 300

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active

053324757

ABSTRACT:
The present invention relates to a process for cross-linking a proteinaceous material. The process comprises: i) soaking the material to be cross-linked in an agueous solution of high osmolality; ii) incubating the material in an agueous buffer including an amount of a photooxidative catalyst sufficient to catalyze photooxidation of the material; and iii) irradiating the material and the catalyst of step (i) with light that includes a range of wavelengths selectively absorbed by the catalyst. Irradiation is effected under conditions such that cross-linking of the material occurs. In a further embodiment, the present invention relates to a cross-linked product produced by the above-described method.

REFERENCES:
patent: 3152976 (1964-10-01), Kuntz
patent: 4835258 (1989-05-01), Hollenberg et al.
patent: 5024742 (1991-06-01), Nesburn et al.
Chemical Abstracts, vol. 72, No. 9, Mar. 2, 1990, p. 24, Abstract No. 38990x, Columbus, Ohio, US; C. Gowri, et al., "Photooxidation of collagen in the presence of methylene blue", Leather Sci. (Madras) 1969, 16(8), 297-300.

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