Cross-linked quaternary ammonium derivatives of poly(N, N-dialky

Details Cross-linked quaternary ammonium derivatives of poly(N, N-dialky Cross-linked quaternary ammonium derivatives of poly(N, N-dialky

1994-06-01

1995-10-31

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 7818, 424 7812, 424439, 424441, 424456, 514824, 5253291, A61K 31785, C08F 802, C08F12602, C08J 324

Patent

active

054627303

ABSTRACT:
The invention concerns novel cross-linked poly(N,N-dialkylallyl)ammonium polymer materials containing quaternary propylammonium structural units which are effective in lowering elevated plasma levels of low density lipoproteins and lipoid components thereof, such as cholesterol, and which are of value in the treatment of conditions in which such elevated plasma levels are associated, for example, various vascular diseases. The invention also provides methods for the manufacture of the polymer materials and various intermediates for use in such manufacture.

REFERENCES:
patent: 4167610 (1979-09-01), Bolto et al.

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