Cross-linked polysaccharide drug carrier

Details Cross-linked polysaccharide drug carrier Cross-linked polysaccharide drug carrier

2005-10-11

2005-10-11

Maier, Leigh C. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S054000, C514S056000, C536S021000, C536S053000, C536S112000

Reexamination Certificate

active

06953784

ABSTRACT:
A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.

REFERENCES:
patent: 4931546 (1990-06-01), Tardy et al.
patent: 5128326 (1992-07-01), Balazs et al.
patent: 5645587 (1997-07-01), Chanda et al.
patent: 5677276 (1997-10-01), Dickerson et al.
patent: 5731298 (1998-03-01), Reinmuller
patent: 5904717 (1999-05-01), Brekke et al.
patent: 6303585 (2001-10-01), Spiro et al.
patent: 6378527 (2002-04-01), Hungerford et al.
patent: 6683064 (2004-01-01), Thompson et al.
patent: 96/41813 (1996-12-01), None
patent: 97/22371 (1997-06-01), None
FranssonBiochimica et Biophysioca Acta1976, 106-115.
Streitwieser et al. Introduction to Organic Chemistry, Macmillan Publishing Company, Inc., New York, 1976, pp. 378-381.

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