Cross-linked polyethylene oxide coatings to improve the biocompa

Details Cross-linked polyethylene oxide coatings to improve the biocompa Cross-linked polyethylene oxide coatings to improve the biocompa

1995-11-29

1997-07-08

Dudash, Diana

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Implantable permanent prosthesis

427536, 427337, 427491, B05D 306, B05D 310

Patent

active

056458827

ABSTRACT:
Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized end-capped PEO which is attached at one end to the medical device. The PEO compounds are then exposed to a high energy source for a time sufficient to cause the PEO compounds to form a cross-linked, insoluble network. These PEO coatings am able to survive ethylene oxide sterilization procedures with minimal loss of protein or cell repulsion ability.

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