Cross-linked polyethylene oxide coatings to improve the biocompa

Details Cross-linked polyethylene oxide coatings to improve the biocompa Cross-linked polyethylene oxide coatings to improve the biocompa

1994-11-16

1996-04-16

Prebilic, Paul B.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

623 6, 427 21, 427 227, A61F 202, A61F 216

Patent

active

055078044

ABSTRACT:
Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized end-capped PEO which is attached at one end to the medical device. The PEO compounds are then exposed to a high energy source for a time sufficient to cause the PEO compounds to form a cross-linked, insoluble network. These PEO coatings are able to survive ethylene oxide sterilization procedures with minimal loss of protein or cell repulsion ability.

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Product Brochure from Advanced Surface Technology, Inc., "Biophilic.TM. Coating" (no date).

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