Cross-linked glycopeptide-cephalosporin antibiotics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Reexamination Certificate

active

07405199

ABSTRACT:
This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.

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Pavlov, et al., A New Type of Chemical Modification of Glycopeptides Antibiotics: Aminomethylated Derivatives of Eremomycin and Their Antibacterial Activity, The Journal of Antibiotics, 1997, vol. 50, No. 6, pp. 509-513.
U.S. Appl. No. 09/457,926, filed Dec. 8, 1999, Christensen et al.

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