Cross-linked derivatives of hyaluronic acid

Details Cross-linked derivatives of hyaluronic acid Cross-linked derivatives of hyaluronic acid

2006-10-24

2006-10-24

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S053000, C536S054000, C536S055100, C536S055200, C536S055300, C536S123100, C536S124000

Reexamination Certificate

active

07125860

ABSTRACT:
The present invention describes a new class of cross-linked derivatives of partially N-deacetylated hyaluronic acid or derivatives thereof, comprising at least one repeating unit of formula (I) hereinafter depicted and a process for the preparation of said cross-linked derivatives, comprising a multicomponent condensation reaction involving the carboxy groups and the amino groups originating from a partial N-deacetylation of hyaluronic acid or derivatives, together with an aldeyde and an isocyanide. The derivatives thus obtained can be used, alone or in association with biologically and/or pharmacologically active substances, for the preparation of pharmaceutical compositions, biomaterials, surgical and healthcare articles, slow release systems and for the coating of biomedical objects.

REFERENCES:
patent: 5874417 (1999-02-01), Prestwich et al.
patent: 0 466 966 (1992-01-01), None
de Nooy et al., “Ionic Polysaccharide Hydrogels via the Passerini and Ugi Multicomponent Condensations: Synthesis, Behavior and Solid-State NMR Characterization,” Biomacromolecules 1:259-267 (2000).
de Nooy et al., “Versatile Synthesis of Polysaccharide Hydrogels Using the Passerini and Ugi Multicomponent Condensations,” Macromolecules 32:1318-1320 (1999).

Affiliated with

Also associated with

Rating

Cross-linked derivatives of hyaluronic acid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cross-linked derivatives of hyaluronic acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cross-linked derivatives of hyaluronic acid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3697618