CRFR2 selective ligands

Details CRFR2 selective ligands CRFR2 selective ligands

2006-11-28

2006-11-28

Tsang, Cecilia J. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600, C514S009100, C514S011400, C530S300000, C530S317000, C530S324000

Reexamination Certificate

active

07141546

ABSTRACT:
CRF peptide analogs that bind to CRFR2 with an affinity far greater than they bind to CRFR1. These analogs exhibit CRF antagonist activity, and they can be based upon the native structures of sauvagine, CRF, and urocortin.

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