Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Cyclic peptides
Reexamination Certificate
2009-02-06
2010-12-14
Tsang, Cecilia (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Cyclic peptides
Reexamination Certificate
active
07851588
ABSTRACT:
CRF peptide analogs that bind to CRFR1 with an affinity far greater than they bind to CRFR2. Some of these analogs exhibit CRF agonist activity. One exemplary analog that may be made by solid-phase synthesis is:(cyclo 31-34)[Ac-Pro4,D-Phe12,Nle18,21,Glu31,Lys34]-sucker urotensin(4-41).
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Gulyas Jozsef
Perrin Marilyn H.
Rivier Jean E. F.
Vale, Jr. Wylie W.
Fitch Even Tabin & Flannery
Heard Thomas S
The Salk Institute for Biological Studies
Tsang Cecilia
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