Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-06
1998-08-18
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5482628, 5482648, 5482658, A61K 3141, C07D24914
Patent
active
057959056
ABSTRACT:
CRF receptor antagonists are disclosed. Such receptor antagonists are thiadiazole-, pyrimidine-, triazine-, and triazole-containing compounds substituted with both a C3-C14 monocyclic or fused, homoaryl or heteroaryl group and a substituted amine group. The CFR receptor antagonists have utility in the treatment of a variety of disorders, including disorders associated with the hypersecretion of CRF.
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Chen Chen
McCarthy James R.
Ramphal John Y.
Webb Thomas R.
Whitten Jeffrey P.
Neurocrine Biosciences Inc.
Ray Deepak R.
Shah Mukund J.
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