Creba Isoform

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 43525231, 43525421, 536 232, 536 2315, C07H 2104, C12P 121, C12P 1521, C12P 1563

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active

058540164

ABSTRACT:
The present invention relates generally to a novel CREBa polypeptide isoform, polynucleotides encoding the polypeptide, expression constructs comprising the polynucleotides, host cell transformed or transfected with the polynucleotides, methods for producing the polypeptide, and methods to identify inhibitors of binding between the CREBa and other polypeptides or polynucleotides.

REFERENCES:
Ahmed, "Significance of the Casein Kinase System in Cell Growth and Proliferation with Emphasis on Studies of the Androgenic Regulation of the Prostate," Cell. Mol. Biol. Res. 40:1-11 (1994).
Ausubel, "Immunoaffinity Chromatography," et al., Current Protocols in Molecular Biology, John Wiley & Sons (1993), pp. 10.11.8-10.11.22.
Bartel, et al., "Using the two-hybrid system to detect protein--protein intractions,"Cellular Ineractions in Development: a Practical Approach, Hartley (ed.), IRL Press; Oxford, pp. 153-179 (1993).
Chen and Okayama, "Calcium Phosphate-Mediated Gene Transfer: A Highly Efficient Transfection System for Stably Transforming Cells With Plasmid DNA," Biotechniques 6:632-638 (1988).
Chou and Blenis, "The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling," Curr. Opin. Cell. Biol. 7:806-814 (1995).
Digman, et al., "Accurate transcription initiation by RNA polymerase II in a soluable extract form isolated mammalian nuclei,"Nucl. Acids Res. 11:1475-1489 (1983).
Durfee, et al., "The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit," Genes and Development 7:555-569 (1993).
Hall and Peters, "Genetic Alterations of Cyclins, Cyclin-Dependent Kinases, and Cdk Inhibitors in Human Cancer,"Adv. Cancer Res. 68:67-108 (1996).
Hollenberg, et al., "Identification of a New Family of Tissue-Specific Basic Helix-Loop-Helix Proteins with a Two-Hybrid System," Mol. Cell. Biol. 15: 3813-3822 (1995).
Kapecchi, et al., "Altering the Genome by Homologos Recombintion," Science 244: 1288-1292 (1989).
Marshall, "Opportunities for pharmacological intervention in the ras pathway," Ann. Onocol. 6:Suppl. 1:63-67 (1995).
Pollock and Treisman, "A sensitive method for the determination of protein-DNA binding specifities," Nucleic Acids Res. 18:6197-6204, (1900).

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