Creation of a biological atrioventricular bypass to...

Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Cardiovascular system – other than umbilical artery or vein

Reexamination Certificate

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C435S366000, C435S455000

Reexamination Certificate

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07968126

ABSTRACT:
A method of creating an atrioventricular bypass tract for a heart comprises growing mesenchymal stem cells into a strip with two ends, attaching one end of the strip onto the atrium of the heart, and attaching the other end of the strip to the ventricle of the heart, to create a tract connecting the atrium to the ventricle to provide a path for electrical signals generated by the sinus node to propagate across the tract and excite the ventricle.

REFERENCES:
patent: 6387369 (2002-05-01), Pittenger et al.
patent: 6690970 (2004-02-01), Taheri et al.
patent: 2002/0155101 (2002-10-01), Donahue et al.
patent: 2004/0137621 (2004-07-01), Rosen et al.
Connexin 40 from GenBank Accession No. NP—005257, pp. 1-4. Accessed May 14, 2009.
Connexin 43 from GenBank Accession No. NP—000156, pp. 1-3. Accessed May 14, 2009.
Connexin 45 from GenBank Accession No. NP—005488, pp. 1-3. Accessed May 14, 2009.

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