Electrolysis: processes – compositions used therein – and methods – Electrolytic analysis or testing – Involving enzyme or micro-organism
Reexamination Certificate
2008-03-28
2010-10-19
Noguerola, Alex (Department: 1795)
Electrolysis: processes, compositions used therein, and methods
Electrolytic analysis or testing
Involving enzyme or micro-organism
C205S792000
Reexamination Certificate
active
07815788
ABSTRACT:
In a method for calibrating a biosensor for the amperometric determination of creatinine in biological liquids, consisting of one electrode system each for measuring the concentrations of creatinine and creatine, with at least two calibration solutions being used, the electrode system for measuring the creatinine concentration is calibrated with a creatinine solution which, prior to the calibration measurement, was mixed in the form of an acidic solution with an alkaline buffer solution, and the electrode system for measuring the creatine concentration is calibrated with a solution in which creatinine and creatine are at a thermodynamic equilibrium.
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English language translation of Miyashiro JP58061459 A, May 2007.
Edgar et al. (“Equilibrium between creatine and creatinine in aqueous solution. The effect of hydrogen ion,” Journal of the American Chemical Society (1925), 47, 1179-88).
Wikipedia entries for “Good's buffers” and “MES” downlo9aded Apr. 24, 2007.
Florian Gernot
Kroneis Herbert
Noormofidi Taghi
Schaffar Bernhard
Steinbock Wolf-Dietrich
McDonnell Boehnen & Hulbert & Berghoff LLP
Noguerola Alex
Roche Diagnostics Operations Inc.
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