Covalently reactive transition state analogs and methods of...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

Reexamination Certificate

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C530S350000, C435S188500

Reexamination Certificate

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06855804

ABSTRACT:
Improved methods for the production, selection and inhibition of catalytic antibodies are disclosed.

REFERENCES:
patent: 5420328 (1995-05-01), Campbell
patent: 5952462 (1999-09-01), Powell et al.
patent: WO 9529691 (1995-11-01), None
Paul, S., et al. (2003) J. Biol. Chem. 278(22), 20429-20435.*
Hanson, J.E., et al. (1989) Biochem. 28, 6294-6305.*
Hirschmann, R., et al. (1994) Science 265, 234-237.*
Takahashi, N. et al. “Improved Generation of Catalytic Antibodies by MRL/MPJ-Ipr/Ipr Autoimmune Mice”; Journal of Immunological Methods; 235;(2000) 113-120.
Wirsching, P., et al. “Reactive Immunization Science”; 270 Dec. 15, 1995 1775-1782.
Mei, S. et al. “Vasoactive Intestinal Peptide Hydrolysis by Antibody Light Chains” The Journal of Biological Chemistry; 226; 24, Aug. 25, 1991; 15571-15574.

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