Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-07-09
1993-10-26
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 78, 514557, 514885, 530300, 530329, 530331, A61K 3100, A61K 31685, A61K 3119, A61K 3702
Patent
active
052566412
ABSTRACT:
This invention relates to methods of facilitating the entry of peptides into cells and targeting such peptides to specific organelles within the cell. The invention provides methods for delivering and specific targeting of antigenically-active peptides to cells for the specific production of immunological reactivity against such peptides, as well as compositions and pharmaceutical compositions of matter comprising such peptides. This invention thereby provides improved methods for vaccine production and in vivo vaccination against pathogenic microorganisms. Methods for alleviating autoimmune disease and ameliorating tissue and organ transplant rejection using such conjugates are also provided.
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Malkovsky Miroslav
Stowell Michael H. B.
Yatvin Milton B.
Rollins John W.
State of Oregon
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