Covalent cyanine dye oligonucleotide conjugates

Details Covalent cyanine dye oligonucleotide conjugates Covalent cyanine dye oligonucleotide conjugates

1994-07-18

1997-01-28

Houtteman, Scott W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 266, 2504581, C12Q 168, C07H 2104

Patent

active

055976964

ABSTRACT:
The present invention relates to conjugates of a cyanine dye and an oligonucleotide. When these conjugates hybridize or bind to a target, a detectable increase in fluorescence intensity or change in fluorescence polarization is observed.

REFERENCES:
patent: 4883867 (1989-11-01), Lee et al.
Haralambidis et al. (1987) Nucleic Acids Res. 15(12):4857-4876.

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