Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1994-09-28
1996-02-13
Fay, Zohreh
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
514 2, A61K 3846, A61K 3700
Patent
active
054909805
ABSTRACT:
Transglutaminase crosslinks proteins by catalyzing the formation of isopeptide bonds between lysine and glutamine residues. Transglutaminase may be used to crosslink beneficial actives containing an amine moiety to glutamine residues in skin, hair or nails. A variety of beneficial actives, e.g., sunscreens, antimicrobial compounds, skin conditioning agents, hair conditioning agents, anti-inflammatory compounds, antioxidants, coloring agents, perfumes, insect repellants, can thus be delivered to human skin, hair, or nails.
REFERENCES:
Derwent Abstract of JP 3213574. (1991).
Derwent Abstract of JP 3095109. (1991).
Derwent Abstract of JP 3083908. (1991).
Derwent Abstract of JP 3038511. (1991).
Derwent Abstract of JP 2204407. (1990).
Derwent Abstract of JP 2169511. (1990).
Dutton, A. et al., "Crosslinking and Labeling of Membrane Proteins by Transglutaminase-catalyzed Reactions" Proc. Nat. Acad. Sci. USA, vol. 72, No. 7, Jul. 1975, pp. 2568-2571.
Bailey Peter L.
Pocalyko David J.
Richardson Norman K.
Schilling Kurt M.
Chesebrough-Pond's USA Co. Division of Conopco, Inc.
Fay Zohreh
Mitelman Rimma
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