Coupling reagent and method

Details Coupling reagent and method Coupling reagent and method

1995-05-05

1997-04-01

Lukton, David

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Synthesis of peptides

530333, 530338, 530339, 530344, A61K 3802

Patent

active

056166877

ABSTRACT:
A solid phase coupling reagent for amide formation, comprising insoluble polymer bearing pendant side chains, said side chains each comprising a terminal portion having the formula ##STR1## wherein Y.sup.- is a counteranion and n is independently an integer from 2 to 6; and a method of making amides employing the coupling reagent.

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