Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1992-01-13
1993-05-04
Nucker, Christine M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530327, 530345, 530394, 530395, 530405, 530406, 530409, 530410, 424 8591, 514 2, 514 8, 514 12, 514 21, 536 64, 435961, C07K 1702, C07K 1528, A61K 3944, A61K 3704
Patent
active
052083233
ABSTRACT:
The present invention relates to antitumor compounds of the formula I: ##STR1## wherein M is selected from the group consisting of an hydrogen atom, a peptide residue, and a protein residue linked to the carbon atom via the amino residue of .epsilon.-lysine present therein which can be an antibody used to target the anti-tumor agent to the malignant cells, and R can be an antitumor agent such as daunorubicin, doxorubicin, or an epirublicin derivative.
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Page Michel
Thibeault Denis
Kim Kay K.
Nucker Christine M.
Universite Laval
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