Measuring and testing – Liquid analysis or analysis of the suspension of solids in a... – Content or effect of a constituent of a liquid mixture
Reexamination Certificate
2006-04-18
2006-04-18
Larkin, Daniel S. (Department: 2856)
Measuring and testing
Liquid analysis or analysis of the suspension of solids in a...
Content or effect of a constituent of a liquid mixture
C073S061520, C073S061580, C422S070000, C436S161000, C436S173000, C210S656000
Reexamination Certificate
active
07028537
ABSTRACT:
A hyphenated technique based on the combination of high performance liquid chromatography (HPLC), electrochemical (coulometric) oxidation (EC) and electrospray ionization (ESI)- or atmospheric pressure chemical ionization (APCI)-mass spectrometry (MS), allows access of selected groups of low and medium polarity analytes to ESI- or APCI-mass spectrometry after HPLC by electrochemical treatment of the sample.
REFERENCES:
patent: 4343767 (1982-08-01), Long et al.
patent: 5399256 (1995-03-01), Bohs et al.
“Liquid chromatography with post-column electrochemical treatment and mass spectrometric detection of non-polar compounds” Diehl et al. ,Analyst, 2001 126, 288-290.
“Electrospray as a Controlled-Current Electrolytic Cell: Electrochemical Ionization of Neutral Analytes for Detection by Electrospray Mass Spectrometry” Van Berkel ZhouAnalytical Chemistry, vol. 67, No. 21Nov. 1, 1995 p. 3958-3964.
“On-Line Investigation of the Generation of Nonaqueous Intermediate Radical Cations by Electrochemistry/Mass Spectrometry” Zhang and Brajter-TothAnal Chem., 2000, 72, 2533-2540.
“On-Line Probe for Fast Electrochemistry/Electrospray Mass Spectrometry. Investigation of Polycyclic Aromatic Hydrocarbons” Xu et al.Anal. Chem, 1996, 68, p. 4244-4253.
“Electrochemical Polymerization of Aniline Investigated Using On-Line Electrochemist Electrospray Electrospray Mass Spectrometry” Deng and Van BerkelAnal. Chem, 1999, 71, p. 4284-4293.
“Electrochemically Modulated Preconcentration and Matrix Elimination for Organic Analytes Coupled On-Line with ElectrosprayMass Spectrometry” Pretty et al.Anal Chem., 72, p. 2066-2074.
“The ESA electrical cell coupled with electrospray ionization mass spectrometry” U. Jurva Poster presented 990616 at the 47th ASMS Conference on Mass Spectrometry and Allied Topics, Dallas, TX.
“Electrochemistry On-Line with Electrospray: Insights into Oxidative Metabolism of Tamoxifen” Deng and Van Berkel Chemical and Analytical Sciences Division, Oak Ridge National Laboratory Oak Ridge, TN 37831-6365, 2 pg. independent article.
“Comparison of Detection Limits of Electrochemistry/Electrospray-MS and APCI-MS” Zhang and Cole, Department of Chemistry, University of New Orleans, Lakefront New Orleans, LA 70148, 2pg independent article.
“An Electrochemical Cell for On-Line Electrochemistry/Mass Spectrometry” Corazon et al.Anal. Chem., 1997, 69, p. 5067-5072.
“Electrochemistry On Line with Mass Spectrometry Insight into Biological Redox Reactions” Volk et al.Anal. Chem., 1992, 64, p. 21A-33A.
“Effect of Mobile Phase Composition on the Electrochemical Cell Conversion Efficience in Electrochemistry/Mass Spectrometry” Regino et al.,Analytica Chimica Acta, 369, 1998, p. 253-262.
“Detection of the Oxidative Produces of 3-Hydroxykynurenine Using High-Performance Liquid Chromatology-Electrochemical Detection- Ultraviolet Absorption Detection-Electron Spin Resonance Spectrometry and High-performance Liquid Chromatography- Electrochemical Detection-Ultraviolet absorption detection-Mass Spectrometry” Iwahashi and Ishii,Journal of Chromatography A, 773, 1997, p. 23-31.
“3-Hydroxyanthranillc Acid-Derived Compounds Formed Through Electrochemical Oxidation” Iwahashi,Journal of Chromatography B, 736, 1999, p. 237-245.
“Electrochemical Thermospray Mass Spectrometry Instrumentation for Coupling Electrochemistry to Mass Spectrometry” Hambitzer et al.,Analytical Chemistry70, 1998, p. 838-842.
“A Role for Electrospray Mass Spectrometry in Electrochemical Studies” Bond et al.,Anal. Chem.67, 1995, p. 1691-1695.
“In Vetro Mimicry of Metabolic Oxidation Reactions by Electrochemistry/ Mass Spectrometry” Jurva et al.,Rapid Commun. Mass Spectrum14, 2000, p. 529-533.
“Characterization of Solution-Phase and Gas-Phase Reactions in On-Line Electrochemistry-Thermosprey Tandem Mass Spectrometry” Volk et al.,Journal of Chromatography474, 1989, p. 231-243.
“In Vitro Mimicry of Metabolic Oxidation Reactions by Electrochemistry/Mass Spectrometry” Poster presented at the 15th IMS Conference in Barcelona 28/8-31/8 2000, Jurva et al.
“On-Line Electrochemistry/Thermospray/Tandem Mass Spectrometry as a New Approach to the Study of Rodox Reaction: The Oxidation of Uric Acid” Volk et al.,Anal. Chem.61, 1989, p. 1709-1717.
“Electrochemical Oxidation and Nucleophillic Addition Reactions of Metallocenes in Electrospray Mass Spectrometry” Xu et al.,Anal. Chem.66, 1994, p. 119-125.
“On-Line Linear Sweep Voltammetry-Electrospray Mass Spectrometry” Lu et al.,Anal. Chem.69, 1997, p. 2478-2484.
“Electrochemistry/Thermospray/Tandem Mass Spectrometry In the Study of Biooxidation of Purines” CorrespondenceAnal Chem.60, 1988, p. 720-724.
“Electrochemistry Combined On-Line with Electrospray Mass Spectrometry” Zhou et al.,Anal Chem.67, 1995, p. 3643-3649.
“Electrochemically Modulated Liquid Chromatography Coupled On-Line with Elecyrospray Mass Spectrometry” Deng et al.,Anal Chem.72, 2000, p. 2641-2647.
Diehl Georg
Hayen Heiko
Karst Uwe
ESA Biosciences, Inc.
Hayes & Soloway P.C.
Larkin Daniel S.
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