Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1986-05-29
1989-08-29
Kepplinger, Esther M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
424 11, 435 7, 435 68, 435272, 436547, 514 6, 530329, 530330, 530331, 530345, 530387, 530388, 530404, 530405, 530406, 534 10, 534573, 534692, 548341, 548542, C07K 300
Patent
active
048618691
ABSTRACT:
This invention relates to bifunctional coupling agents useful in forming conjugates with biologically useful molecules, such as antibodies. These conjugates can be complexed with radionuclide metal ions to provide materials useful for in vivo diagnostic and therapeutic applications.
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Dean Richard T.
Nicolotti Robert A.
Kepplinger Esther M.
Mallinckrodt Inc.
Wieder Stephen C.
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