Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1988-11-23
1992-01-21
Kepplinger, Esther L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
548341, 548542, 562575, 424 11, 424 8591, C07K 300
Patent
active
050829300
ABSTRACT:
This invention relates to bifunctional coupling agents useful in forming conjugates with biologically useful molecules, such as antibodies. These conjugates can be complexed with radionuclide metal ions to provide materials useful for in vivo diagnostic and therapeutic applications.
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Dean Richard T.
Nicolotti Robert A.
Kepplinger Esther L.
Mallinckrodt Medical Inc.
Spiegel Carol A.
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