Coupling agents comprising a photolabile protecting group...

Combinatorial chemistry technology: method – library – apparatus – Method of creating a library – Solid-phase synthesis or particular method of cleavage from...

Reexamination Certificate

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C506S003000, C548S542000

Reexamination Certificate

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07846875

ABSTRACT:
The invention relates to compounds comprising a photolabile protecting group and to the use thereof as coupling agents for the functionalisation of solid supports. The invention also relates to the solid supports functionalised by said compounds and to the use of same for the immobilisation of biological molecules of interest, such as nucleic acid molecules.

REFERENCES:
patent: 6686461 (2004-02-01), Schwartz et al.
patent: 6965040 (2005-11-01), Gao et al.
patent: WO 97/39151 (1997-10-01), None
Podyminogin et al (2001 Nucleic Acids Research 29:5090-5098).
Bhushan K.R. et al., “Synthesis of photoliable 2-(2-nitrophenyl)propyloxycarbonyl protected amino acids”,Tetrahedron Letters, Elsevier Science Publishers, vol. 44, No. 47, Nov. 17, 2003, pp. 8585-8588.
Acedo M. et al., “N-2-(2,4-dinitrophenyl)ethyloxycarbonyl-Amino Acids, New Base Labile Protected Derivatives Suitable for Solid-Phase Peptide Synthesis”,Tetrahedron Letters, vol. 33, No. 34, 1992, pp. 4989-4992.

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