Coumarin derivatives as ion channel openers

Details Coumarin derivatives as ion channel openers Coumarin derivatives as ion channel openers

2006-01-18

2010-02-16

Andres, Janet L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S283000

Reexamination Certificate

active

07662975

ABSTRACT:
The present invention is directed to novel coumarin derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders related to ion channels such as potassium channels.

REFERENCES:
patent: 4749798 (1988-06-01), Gandolfi et al.
patent: 4845242 (1989-07-01), Powers et al.
patent: 6331562 (2001-12-01), Bhagwat et al.
patent: 2005/0080082 (2005-04-01), Hewawasam et al.
patent: WO 03/043977 (2003-05-01), None
patent: WO 2004/035002 (2004-04-01), None
PCT International Search Report for International Appln No. PCT/US2006/001927 dated Jul. 31, 2006.
Edwards, G. et al.: “Structure—activity relationships of K+channel openers”; TiPS, Oct. 1990 11: 417-422.
Sato, H. et al.: “Vasorelaxant Activity of 2-fluoroalkyl-6-nitro-2H-1-Benzopyran-4-carbothioamide and -carboxamide K+Channel Openers”; Bioorganic & Med. Chem. Ltrs. (1995) 5(3): 233-236.
Taka, N. et al.: “6-Substituted 2,2-Bis(fluoromethyl)-benzopyran-4-carboxamide K+Channel Openers”; Bioorganic & Med. Chemistry (2000) 8: 1393-1405.
Database Beilstein, Beilstein Institut zur Furderung der Wissenschaften, Frankfurt/Main, DE; XP002392763; J. Indian Chem. Soc., vol. 21 (1994) p. 44.
Database CA [Online] Chemical Abstracts Service Columbus, Ohio, US; Thakar, K.A.: “Condensation of m-halophenols with acetonedicarboxylic acid in presence of sulfuric acid”; XP002392764; J. Indian Chem. Soc. (1963), 40(5), p. 397.
Database Chemcats [Online], Chemical Abstracts Serivce, Columbus, Ohio, US; XP002392765; Enamine Screening Library, Jan. 24, 2006. Abstract.

Affiliated with

Also associated with

Rating

Coumarin derivatives as ion channel openers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Coumarin derivatives as ion channel openers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Coumarin derivatives as ion channel openers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4212295