Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-12-09
1988-03-15
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548253, A61K 3141, C07D25704
Patent
active
047313757
ABSTRACT:
A chromene derivative having the general formula (I): ##STR1## wherein n is 1 to 5 and --O--CH.sub.2).sub.n CO.sub.2 H group is attached to 5-position, 6-position, 7-position or 8-position, or salts thereof, a process for preparing the same and antiallergic agents containing the same.
The compounds of the present invention inhibit the immunological release of chemical mediators such as SRS-A and histamine from mast cell and have an excellent effect in preventing and treating the various allergic diseases such as allergic asthma, allergic dermatitis, allergic nasitis, hives, allergic enteritis and allergic conjunctivitis, especially allergic asthma.
REFERENCES:
patent: 3600437 (1971-08-01), Marshall
patent: 4406908 (1983-11-01), Matsuda et al.
Awaji Toshikazu
Hiyama Yoshiyuki
Kuriyama Kiyoshi
Nakano Jun
Okuda Toshiaki
Hollrah Glennon H.
Kaken Pharmaceutical Co. Ltd.
Springer D. B.
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