Coumarin derivative having antitumor activity

Details Coumarin derivative having antitumor activity Coumarin derivative having antitumor activity

2011-03-01

2011-03-01

Chandrakumar, Nizal S (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07897792

ABSTRACT:
The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof:wherein: X is selected from heteroaryl etc., Y1and Y2are selected from —N═ etc., Y3and Y4are selected from —CH═ etc., A is selected from sulfamide etc., R1is selected from hydrogen etc., and R2is selected from C1-6alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.

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