Cosolvent formulations

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai

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424236, A61K 3159, A01N 4500

Patent

active

061367990

ABSTRACT:
Stable pharmaceutical formulations of a therapeutic agent, a low molecular weight alcohol and a glycol derivative are disclosed. Preferred formulations include 19-nor-1.alpha.,3.beta.,25-trihydroxy-9,10-secoergosta-5,7(E),22(E)-triene .

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Bertino et al., Stability of an extemporaneous formulation . . . , American J. of Hosp. Pharmacy, V38(12), p. 1932-1933, 1981.
mortensen et al., Toxicity of 1,25-dihydroxyvitamin D3 . . . , Journal of Investigative Dermat . . . , V 1(1), p. 60-63, 1996.
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Bertino et al., Stability of an extra . . . , American J. of Hosp. Pharmacy, vol. 38/12, pp. 1932-1933, (1981).

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