Cosmetic pharmaceutical or foodstuff composition comprising an a

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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424401, 424 59, 424 63, 424 65, 424 70, 424DIG4, 424DIG13, 4284022, 514827, 514852, 514864, A61K 9127

Patent

active

052681807

ABSTRACT:
This composition consists in an aqueous dispersion D, lamellar structure lipid vesicles encapsulating an aqueous phase E; it is characterised by the fact that the lipid phase forming the layers of the said vesicles is at least partly made up of a compound as formula (I): ##STR1## wherein R represents a linear saturated on unsaturated hydrocarbonated chain containing 9 to 17 carbon atoms. The compounds (I) have the advantage that they are easily biodegradable and of very low cytotoxicity.

REFERENCES:
Kiwada Chem. Pharm. Bull 33(2) 753, 1985.
Schenk et al, "Studies on sucrose-palmitate-stearate-containing vesicles encapsulating the cytostatic drug methylglyoxal-bis-quanyl-hydra-zone", Die Pharmazie, vol. 45, No. 10, Oct. 1990, pp. 747-749.
Derwent File Supplier WPIL (L), 1986 AN=86-282499.
Derwent File Supplier WPIL (L), 1989 AN=89-073938.
Kiwada et al, "Application of synthetic alkyl glycoside vesicles as drug carrier. I. Preparation and physical properties".
French Search Report of FR 90 13917.

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