Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Patent
1998-11-06
2000-11-28
Dudash, Diana
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
424 60, 424 64, 424 68, 424 69, 514938, 514944, A61K 700, A61K 744, A61K 7025, A61K 738, A61K 7035
Patent
active
061532045
DESCRIPTION:
BRIEF SUMMARY
The present invention relates to cosmetic or pharmaceutical preparations with a reduced feeling of stickiness, to a process for their preparation and to the use of active ingredients for reducing the feeling of stickiness of cosmetic preparations.
The main aim of skin care in the cosmetics sense is to strengthen or rebuild the skin's natural function as a barrier against environmental influences (e.g. dirt, chemicals, microorganisms) and against the loss of endogenous substances (e.g. water, natural fats, electrolytes).
If this function becomes impaired, increased resorption of toxic or allergenic substances or infection by microorganisms may result, leading to toxic or allergic skin reactions.
Another aim of skin care is to compensate for the loss by the skin of grease and water caused by daily washing. This is particularly important if the natural regeneration ability is inadequate. Furthermore, skin-care products should protect against environmental influences, in particular against sun and wind, and delay skin ageing.
Medicinal compositions usually comprise one or more medicaments in an effective concentration. For the sake of simplicity, in order to distinguish clearly between cosmetic and medicinal use and corresponding products, reference is made to the legal provisions in the Federal Republic of Germany (e.g. Cosmetics Regulation, Foods and Drugs Act).
Cosmetic or dermatological preparations are frequently in the form of finely dispersed multiphase systems in which one or more fatty or oily phases are present alongside one or more aqueous phases. Of these systems, the actual emulsions are, in turn, the most widespread.
In simple emulsions, one phase contains finely disperse droplets of the second phase, surrounded by an emulsifier shell (water droplets in W/O emulsions or lipid vesicles in O/W emulsions). In a multiple emulsion (second degree), on the other hand, such droplets contain finely disperse droplets of the first phase in emulsified form. These droplets may in turn contain even more finely disperse droplets (third degree multiple emulsion) and so on.
Thus, just as reference is made in the case of simple emulsions to W/O or O/W emulsions (Water-in-Oil or Oil-in-Water), in the case of multiple emulsions reference is made to W/O/W, O/W/O, O/W/O/W, W/O/W/O emulsions and so on.
The droplet diameters of customary emulsions are in the range from approximately 1 .mu.m to approximately 50 .mu.m. Such "macroemulsions" are, without other colouring additives, milky white in colour and opaque. Finer "macroemulsions", whose droplet diameters are in the range from approximately 10.sup.-1 .mu.m to approximately 1 .mu.m, are, again without colouring additives, blueish white in colour and opaque.
Only micellar and molecular solutions having particle diameters of less than approximately 10.sup.-2 .mu.m appear clear and transparent.
The droplet diameter of transparent or translucent microemulsions, on the other hand, is in the range from about 10.sup.-2 .mu.m to about 10.sup.-1 .mu.m. Such microemulsions usually have a low viscosity. The viscosity of many microemulsions of the O/W type is comparable with that of water.
An advantage of microemulsions is that the disperse phase can contain active ingredients in more finely disperse form than in the disperse phase of "macroemulsions". A further advantage is that, because of their low viscosity, they can be sprayed. If microemulsions are used as cosmetics, the corresponding products are distinguished by high cosmetic elegance.
The use of customary cosmetic emulsifiers is in itself acceptable. Nevertheless, emulsifiers, like ultimately any chemical substance, may in certain circumstances cause allergic reactions or reactions based on over-sensitivity of the user.
For example, it is known that certain light dermatoses are triggered by certain emulsifiers, but also by a variety of fats, and simultaneous exposure to sunlight. Such light dermatoses are also called "Mallorca acne".
Emulsifier-free cosmetic preparations, often in the form of light protection preparation
REFERENCES:
patent: 3852475 (1974-12-01), Tarangul
patent: 3998753 (1976-12-01), Antoshkiw et al.
patent: 4981677 (1991-01-01), Thau
Chemical Abstracts, vol. 124, No. 1 (1996), Abstract No. 7401, Trubiano, Paulo C.: The role of specialty food starches in flavor encapsulation and ACS Symp. Ser. (1995), 610 (Flavor Technology) 244-53: ACSMC8; ISSN: 0097-6156 (1995).
Fanger Sabine
Fecht Stephanie von der
Haest Gertrudis
Schneider Gunther
Beirsdorf AG
Berman Alysia
Cerestar Holding B.V.
Dudash Diana
LandOfFree
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