Cosmetic or pharmaceutical composition, especially dermatologica

Details Cosmetic or pharmaceutical composition, especially dermatologica Cosmetic or pharmaceutical composition, especially dermatologica

1994-04-22

1995-12-19

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Topical sun or radiation screening, or tanning preparations

424 74, 4241951, A61K 713, A61K 742

Patent

active

054766516

DESCRIPTION:

BRIEF SUMMARY
This application is the National Phase of PCT/FR92/00444 filed on May 19, 1992.
The present invention relates essentially to a cosmetic or pharmaceutical composition, especially dermatological composition, containing an extract of Cyperus, intended in particular for promoting the pigmentation of the skin or hair, and to the process for its manufacture.
It further relates to the use of an extract of Cyperus for the preparation of such a cosmetic or pharmaceutical composition.
The various species of the genus Cyperus form part of the Cyperaceae family. There are about 650 of these species dispersed throughout the old and new world, with the exception of cold regions. The species of this genus can be determined by reference to Flore complete portative (Pocketbook of Complete Flora) by Gaston Bonnier and G. de Layens, pp. 323 and 324. The Cyperus, also called sedge in English, are annual or perennial herbaceous plants. They generally possess rhizomes. Some also possess tubers. Among the latter, there may be mentioned Cyperus aureus or tuberous sedge, Cyperus esculentus, Cyperus olivaris or Cyperus rotundus L., which are found particularly in France in sandy locations along part of the mediterranean shore. The tubers of Cyperus olivaris or rotundus have been used to treat stomach, lung and bladder diseases. They formed part of the composition of various pharmaceutical preparations such as scorpion oil and theriacal water, which are no longer employed today.
It is also known from the document JP-A-62-234006 that extracts of tubers of Cyperus rotundus have an antiinflammatory activity and can be used for the manufacture of topical cosmetic or pharmaceutical compositions for external application.
Furthermore, it is known from the document U.S. Pat. No. 4,908,207 that extracts of tubers of the plant Cyperus rotundus L., administered orally, can be used to treat immune deficiencies.
It is also known from the document U.S. Pat. No. 4,696,818 that courses of detoxication treatment can be carried out using medicinal compositions containing especially Cyperus rotundus in combination with other plant extracts, particularly extracts of roots of Angelica sinensis.
In addition, the document U.S. Pat. No. 4,826,684 has disclosed a pharmaceutical composition containing a mixture of terpenoids derived from an extract of the tubers of the plant Cyperus rotondus L., which is administered orally for the treatment of diabetes.
The present invention is based on the discovery that extracts of Cyperus, in particular those originating from the rhizomes or tubers, have valuable biological properties which can be utilized in the cosmetic and pharmaceutical fields. In particular, the inventors have observed that these extracts unexpectedly possess a stimulating activity on melanogenesis in the melanocytes present in the skin or the hair follicles, and thus make it possible to promote the pigmentation of the skin or hair as well as to treat disorders of the pigmentation of the skin and hair, more particularly by promoting the biosynthesis of melanin. Very good results in this field have been obtained with extracts of tubers of Cyperus rotundus L.
One object of the present invention is therefore to solve the novel technical problem which consists in providing a novel cosmetic or pharmaceutical composition, especially dermatological composition, intended in particular for promoting the pigmentation of the skin or hair.
A further object of the present invention is to solve the novel technical problem which consists in preparing a novel formulation of a cosmetic or pharmaceutical composition having a good stimulating activity on melanogenesis in the melanocytes present in the skin or in the hair follicles.
A further object of the present invention is to provide a solution to the novel technical problem which consists in providing a plant extract which is particularly easy to obtain and which inherently has a good stimulating activity on melanogenesis in the melanocytes present in the skin or the hair follicles, without it being necessary to i

REFERENCES:
patent: 4390532 (1983-06-01), Stuttgen
patent: 5081151 (1992-01-01), Davies

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