Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1996-07-26
1998-07-07
Dodson, Shelley A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
424401, 514844, 514847, A61K 3578
Patent
active
057764611
ABSTRACT:
Natural skin care composition containing selected hydroxylated vitamin D compounds or their glycosides, which are derived from plant sources (phytovitamins D). The plant extracts must contain a critical minimum concentration of the phytovitamin D (measured in equivalents of 1,25-(OH).sub.2 D in order to induce cell differentiation. In the alternative, phytovitamin D, especially phytovitamin D glycoside, is employed in conjunction with a plant-derived glycosidase.
REFERENCES:
patent: 4410515 (1983-10-01), Holick et al.
patent: 5439935 (1995-08-01), Rawlings et al.
patent: 5476661 (1995-12-01), Pillai et al.
MacLaughlin, et al., "Cultured Human Keratinocytes Cannot Metabolize Vitamin D.sub.3 to 25-hydroxyvitamin D.sub.3 " Federation of European Biochemical Societies, vol. 282, No. 2, (May 1991), pp. 409-411.
Tanaka, et al., "1.alpha., 25-dihydroxycholecalciferol and a human mycloid leukemia cell line (HL-60)," Biochem J, vol. 204, pp. 713-719, Great Britain (1982).
Brinker Anita Marie
Gottlieb Keith Andrew
Mahajan Manisha
Pillai Sreekumar
Rawlings Anthony Vincent
Chesebrough-Pond's USA Co. Division of Conopco, Inc.
Dodson Shelley A.
Williamson Michael A.
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