Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Patent
1997-01-29
1998-12-29
Harrison, Robert H.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
514557, A61K 748
Patent
active
058537422
ABSTRACT:
Inhibitors of lactate dehydrogenase stimulate keratinocyte proliferation and collagen synthesis in cutaneous tissues. The inhibitors are used preferably with certain co-active ingredients such as pyruvic acid, acetic acid, acetoacetic acid, .beta.-hydroxybutyric acid, a Krebs cycle pathway metabolite, an aliphatic saturated or an unsaturated fatty acid containing from 8 to 26 carbon atoms, an .omega.-hydroxy acid containing from 22 to 34 carbon atoms, glutamic acid, glutamine, valine, alanine, leucine, and mixtures thereof.
REFERENCES:
patent: 3823232 (1974-07-01), Galerne
patent: 4018927 (1977-04-01), Voorhees
patent: 4242446 (1980-12-01), Madappally et al.
patent: 4294852 (1981-10-01), Wildnauer
patent: 4322496 (1982-03-01), Esders
patent: 4424234 (1984-01-01), Alderson et al.
patent: 4788196 (1988-11-01), Cross et al.
patent: 4886801 (1989-12-01), Grozinger et al.
patent: 4906488 (1990-03-01), Pera
patent: 5091171 (1992-02-01), Yu et al.
patent: 5250290 (1993-10-01), Giacomoni et al.
patent: 5451405 (1995-09-01), Zhang et al.
patent: 5516793 (1996-05-01), Duffy
patent: 5545402 (1996-08-01), Watkinson
patent: 5547989 (1996-08-01), Chamness
patent: 5554654 (1996-09-01), Yu et al.
patent: 5561107 (1996-10-01), Jaynes et al.
patent: 5561157 (1996-10-01), Yu et al.
patent: 5561158 (1996-10-01), Yu et al.
patent: 5582832 (1996-12-01), Pillai et al.
patent: 5595730 (1997-01-01), Bartolone et al.
patent: 5621006 (1997-04-01), Yu et al.
patent: 5691378 (1997-11-01), Yu et al.
Linnane, Anthony W., et al., "Mitochondrial DNA Mutation and the Ageing Process: Bioenergy and Pharmacological Intervention", Mutation Research, vol. 275, (1992) pp. 195-208.
Nishitani, Koji et al., "Lactate Dehydrogenase Isozyme Patterns of Normal Human Fibroblasts and their In Vitro-transformed Counterparts Obtained by Treatment with Co-60 Gamma-Rays, SV40 or 4-Nitroquinoline 1-oxide", Gann, 72, Apr. 1981, pp. 300-304.
Fleischmajer, Raul, M.D., et al., "Lactate Dehydrogenase Isozyme Patterns in Blister Fluids", The Journal of Investigative Dermatology, vol. 50, No. 5 (1968), pp. 405-408.
Godtfredson et al., "1,6-dihydro-NAD as an Humidity Induced lactate dehydrogenase inhibitor in NADH Preparations", Carlsberg. Res. Comm., 43 (3), (1978), pp. 171-175.
Sheffield et al., "Synthesis of Some 4 Pyridyl Pyruvic Acids as Potential Inhibitors", J. Chem Soc. Perkin Trans. I, No. 20, 1972, pp. 2506-2512.
Meany et al., "N-substituted Oxamates as Inhibitors of Lactate Dehydrogenase", S. Afr. J. Sci, vol. 77, No. 12, (1981), pp. 566-568.
Nisselbaum et al., "Comparison of the Actions of Human Brain, Liver and Heart Lactic Dehydrogenase Variants on Nucleotide Analogues", J. Biol. Chem., 220, 9, (1964).
Warren, "Catalysis of Both Oxidation and Reduction of Glyoxylate by Pig Heart Lactate Dehydrogenase", J. Biol. Chem. 245, 7, (1970).
European Search Report in European Patent Application No. EP 95307967.
Derwent Abstract of Japanese Patent Application No. JP6157284-published Jun. 3, 1994.
CAPLUS Abstract of EP 140589-published May 8, 1985.
Braibanti et al., "Protonation Constant of Oxamic Acid in Aqueous Solution and in Water-Tetrahydrofuran Mixture, at Different Temperatures and Ionic Strengths", Inorg. Chim. Acta, vol. 4, No. 4 (1970) pp. 529-532.
Medline Abstract of Rohde et al., "Contact Lens-Induced Edema In-Vitro Amelioration by Lactate Dehydrogenase Inhibitors", Curr Eye Res., vol. 5, No. 10, (Oct. 1986) pp. 751-758.
CA Abstract of Wang, Jean Fu, "Kinetic and Mechanistic Studies: I. Direct Determination of Self-Exchange Electron-Transfer Rate Constants of Nickel (III, II) Complexes by Nickel-61 EPR Line Broadening. II. Kinetics of the Hydrolysis of 1-Cyanoformamide, Oxamade, and Oxamic Acid in Hydrochloric Acid Solutions", Diss. Abstr. Int. B., vol. 50, No. 3, (1989) p. 931, Full Dissertation Available From University Microfilms Int., Order No. DA8912015, pp. 1-146.
Braibanti et al., "Protonation Constant of Oxamic Acid in Aqueous Solution and in Water-Tetrahydrofuran Mixture, at Different Temperatures and Ionic Strengths", Inorg. Chim. Acta, vol. 4, No. 4, issued 1970, pp. 529-532.
Vermeulen et al., "N-Substituted Oxamates as Inhibitors of Lactate Dehydrogenase", S. Afr. J. Sci., vol. 77, No. 12, issued Dec. 1981, pp. 566-568.
Rohde et al., "Contact Lens-Induced Edema In-Vitro Amelioration by Lactate Dehydrogenase Inhibitors", Curr Eye Res, vol. 5, No. 10, issued Oct. 1986, pp. 751-758.
Wang, Jean Fu, "Kinetic and Mechanistic Studies: I. Direct Determination of Self-Exchange Electron-Transfer Rate Constants of Nickel (III, II) Complexes by Nickel-61 EPR Line Broadening.
II. Kinetics of the Hydrolysis of 1-Cyanoformamide, Oxamide, and Oxamic Aid in Hydrochloric Acid Solutions", Diss. Abstr. Int. B, vol. 50, No. 3, issued 1989, p. 931, Full Dissertion Available.
Bartolone John Brian
Lang Brian David
Penksa Christine Marie
Santhanam Uma
Chesebrough-Pond's USA Co., Division of Conopco
Harrison Robert H.
Mitelman Rimma
LandOfFree
Cosmetic compositions containing lactate dehydrogenase inhibitor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cosmetic compositions containing lactate dehydrogenase inhibitor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cosmetic compositions containing lactate dehydrogenase inhibitor will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1421947