Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ketone doai
Reexamination Certificate
1999-12-14
2003-02-18
Dees, Jose′ G. (Department: 1616)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ketone doai
C424S401000
Reexamination Certificate
active
06521668
ABSTRACT:
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to cosmetic, particularly skin care and treatment, compositions. More particularly, the present invention relates to emulsified cosmetic compositions having certain antioxidants. The antioxidants have been found highly effective in ameliorating or preventing damage to keratinous tissue, such as skin, hair and nails, caused by aggressive environmental substances, such as smoke and other atmospheric pollutants, as well as minimizing or relieving damage caused by ultraviolet radiation.
2. Description of the Prior Art
Skin treatment compositions are extensively described in the art. Emulsified skin treatment compositions are disclosed in U.S. Pat. No. 5,093,109 to Mausner, which issued on Mar. 3, 1992. This Patent provides an anti-aging composition comprising water, an anti-aging agent, a sunscreen, a preservative, a thickener, an antioxidant and an emulsifier. This Patent discloses only “Tenox II”, a product of Eastman Chemical Products, Inc., and ascorbyl palmitate as suitable antioxidants.
U.S. Pat. No. 4,742,066 to Deckner et al., which issued on May 3, 1988, discloses a method for inhibiting the generation of free radicals in the skin. The method comprises applying a composition that may be in the form of an emulsion in which the free radical inhibitor may be ethoxyquin or “Trolox C”. “Trolox C” is a product of Hoffmann-LaRoche.
U.S. Pat. No. 4,603,046 to Georgalas et al. issued on Jul. 29, 1986. This Patent discloses skin treatment compositions having enhanced ultraviolet absorbing properties in the form of oil-in-water emulsions. The essential ingredient is troxerutin and the preferred antioxidant is Tenox II, as disclosed in the Mausner Patent noted above.
U.S. Pat. No. 4,424,234 to Anderson et al., which issued on Jan. 3, 1984, discloses cosmetic formulations for application to the skin. The formulations have a hydroxy alkanoic acid as the essential ingredient and which may contain tocopherol, propyl gallate, ascorbyl palmitate, butylated hydroxy toluene or butylated hydroxy anisole as antioxidants. The compositions, which may be in the form of emulsions, are particularly useful for the treatment of dry skin.
U.S. Pat. No. 5,861,415 to Majeed et al., which issued on Jan. 19, 1999, discloses the pharmaceutical use as a bioprotectant of a mixture of curcumin, demethoxycurcumin and bis-demethoxycurcumin derived from the herb turmeric (
Curcuma longa
). The present invention uses the tetrahydrocurcumin derivatives as antioxidants in an emulsified skin treatment composition.
SUMMARY OF THE INVENTION
It is an object of the present invention to provide cosmetic compositions having certain antioxidants.
It is another object of the present invention to provide such compositions that have a number of benefits in connection with care of and prevention of damage to keratinous tissue. The compositions of this invention may be in the form of gels, lotions, serums, anhydrous sticks, oil based sprays, oil-in-water emulsions or water-in-oil emulsions.
It is a further object of the present invention to provide such compositions that are a strong defense against environmental aggressors such as smoke, smog, ozone, atmospheric pollutants, free radicals and ultraviolet radiation.
These and other objects of the present invention are achieved by a cosmetic composition comprising an essential antioxidant selected from the group consisting of:
(i) hesperetin;
(ii) tetrahydrocurcumin;
(iii) tetrahydrodemethoxycurcumin;
(iv) tetrahydrobisdemethoxycurcumin; and
(v) mixtures of (i), (ii), (iii) or (iv).
The composition may also include one or more emulsifiers, preservatives, thickeners and fragrances.
DESCRIPTION OF THE INVENTION
In accordance with the present invention, there has been discovered cosmetic compositions, preferably in the form of an oil in water emulsion. The term “cosmetic” includes skin care, hair care and nail care compositions. The composition has an essential antioxidant. The essential antioxidant is (i) hesperetin, (ii) tetrahydrocurcumin, (iii) tetrahydrodemethoxycurcumin, or (iv) tetrahydrobisdemethoxycurcumin, or mixtures of two or more of any of the aforesaid antioxidants. The composition may also include one or more emulsifiers, preservatives, and thickeners.
The compositions of the present invention will preferably contain either hesperetin, tetrahydrocurcumin, terahydrodemethoxycurcumin or terahydrobis-demethoxycurcumin, as an essential antioxidant ingredient. More preferably, the composition will contain at least two of these antioxidants. Most preferably, each of the four antioxidants will be present in the cosmetic composition. An even more preferred composition is the mixture of four essential antioxidants, and one or more emulsifiers, preservatives and thickeners in the form of an oil-in-water emulsion.
The compositions of the present invention offer a number of benefits in connection with care and prevention of damage to keratinous tissue. For example, the compositions are quickly absorbed, are not greasy or sticky, and are lightweight. The compositions are suitable for all skin, hair and nail types. They nourish and fortify the skin and improve the skin's appearance, especially dry or sun damaged skin. Also, the compositions provide climatic self-adjusting moisture. Importantly, the compositions provide strong defense against environmental aggressors such as smoke, smog, ozone, atmospheric pollutants, free radicals and ultraviolet radiation. Further, the compositions leave the skin smoother and less fragile. They help to prevent and temporarily protect chafed, cracked or windburned skin. When formulated in one preferred embodiment with one or more sunscreens, the compositions prevent tanning and sunburning, and reduce the risk of premature aging of the skin.
With respect to the essential antioxidants, hesperetin is 4-methoxy-5,7,3-trihydroxyflavone and has the structure:
Hesperetin is used in its pure form in the present compositions, but may be isolated from grapefruit. It is also found in lemons and oranges. In the present compositions, it is present in an amount about 0.01 percentage by weight (wt. %) to about 3.0 wt. %, preferably about 0.1 wt. %, of the total weight of the composition.
Tetrahydrocurcumin, terahydrodemethoxycurcumin and terahydrobis-demethoxycurcumin may be represented by the structure:
When R
1
and R
2
are −OCH
3
, the structure represents tetrahydrocurcumin (THC). When R
1
and R
2
are, respectively, —H and —OCH
3
, the structure represents terahydrodemethoxycurcumin (THDC). When R
1
and R
2
are both —H, the structure represents tetrahydrobisdemethoxycurcumin (THBDC). A preferred antioxidant is a mixture of these three compounds. Such a mixture will typically contain about 75 wt. % to about 95 wt. % of THC, about 8 wt. % to about 20 wt. % of THDC, and about 1 wt. % to about 10 wt. % of THBDC. The mixture, or each of these compounds individually, i.e., THC, THDC or THBDC, may be used in the present compositions in an amount about 0.1 wt. % to about 5.0 wt. %, preferably about 0.75 wt. % to about 1.5 wt. %, and more preferably about 1.0 wt. %.
The emulsifiers may be anionic, cationic, zwitterionic, amphoteric or nonionic when the composition is prepared in the form of an oil in water or water in oil emulsion. Suitable emulsifiers include polymeric acrylate emulsifiers, polyethylene glycol 20 sorbitan monolaurate (Polysorbate 20), polyethylene glycol 5 soya sterol, sorbitan tristearate, polyethylene glycol 40 stearate, sorbitan trioleate, glyceryl, monopalmitate, diethanolamine cetyl phosphate, glyceryl monopalmitate, glyceryl monostearate, polyethylene glycol 100 stearate, cetearyl glucoside, polyethylene glycol 20 stearyl ether (Brij 78, Steareth 20), polyethylene glycol ether of lauryl alcohol (Laureth 23), polysorbate 80 (Tween 80) or lecithin. The composition or formulation will preferably contain a mixture of two or more of these emulsifiers or others that are approved for cosmetic use. The total amount of emulsifier will vary from about 1
Anderson Glen T.
Ptchelintsev Dmitri
Traudt Michael
Avon Products Inc.
Ohlandt Greeley Ruggiero & Perle LLP
Williamson Michael A.
LandOfFree
Cosmetic composition and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cosmetic composition and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cosmetic composition and methods of use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3168660