Cosmetic composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 62, 514880, 514881, 424 70, A61K 706, A61K 748

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active

051853256

ABSTRACT:
A composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises a glycosaminoglycanase inhibitor chosen from aldonomonolactones, alduronomonolactones and acylated monosaccharides, and a cosmetically acceptable vehicle for the inhibitor; the total amount of the inhibitor present in the composition being sufficient to increase hair growth in the rat, when said composition is applied topically thereto over a period of no more than 3 months, by at least 10% more than that obtainable using a control composition from which the said inhibitor has been omitted, in accordance with the Rat Hair Growth Test.

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patent: 4975441 (1990-12-01), Gibson
patent: 5015470 (1991-05-01), Gibson
patent: 5037643 (1991-08-01), Green
patent: 5081151 (1992-01-01), Davis et al.
Errdlender Arch. Lrogverie Pharm. 787-788 (Apr. 1939) Chem Zentr 19401, 3329-3330, Chemical Abs., vol. 36, 1942, Abstract 3910(7).
McOmie, Protective Groups in Organic Chemistry (1973, Plenum Press, New York) pp. 109-111.
Foye, Principals of Medicinal Chemistry (1981, Lea and Febiger, Philadelphia), p. 92.
Clark, The Old Farmer's Almanac, 1988, pp. 82-85.

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