Coryneform bacteria carrying recombinant plasmids and their use

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435115, 4351721, 4351723, 435320, 435840, 435843, 935 29, 935 61, C12N 120

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active

048617229

ABSTRACT:
A genetic sequence coding for the production of a protein having the activity of diaminopimelic acid decarboxylase and having two Pst I cleavage sites in its DNA chain and a molecular weight of 2.9.+-.0.05 Md, is incorporated into a vehicle capable of replication in Coryneform bacteria and used to produce L-lysine by fermentation.

REFERENCES:
patent: 4346170 (1982-08-01), Sano et al.
patent: 4411977 (1983-10-01), Shimazaki
patent: 4442208 (1984-04-01), Tsuchida
patent: 4452980 (1984-06-01), Tsuchida
patent: 4514502 (1985-04-01), Miwa et al.
patent: 4560654 (1985-12-01), Miwa
Chenais et al., "Construction of Hybrid Plasmids Containing the Lys A Gene of Escherichia coli" Studies of Expression in E. coli and Saccharomyces cerevisiae, Chem. Abstracts vol. 95, p. 331 (1981) #146961x.

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