Corynebacterium glutamicum genes encoding...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C435S230000, C435S193000, C435S252320, C435S252100, C536S023200

Reexamination Certificate

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06884614

ABSTRACT:
Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins fromCorynebacterium glutamicumare described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PTS nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated PTS proteins, mutated PTS proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound fromC. glutamicumbased on genetic engineering of PTS genes in this organism.

REFERENCES:
patent: 0 358 940 (1995-09-01), None
patent: WO 9818931 (1998-05-01), None
Dominguez H, et al. Complete sucrose metabolism requires fructose phosphotransferase activity inCorynebacterium glutamicumto ensure phosphorylation of liberated fructose. Applied and Enviroment Microbiology, 1996;62(10):3878-3880.
Lee JK, et al. Nucleotide sequence of the gene encoding theCorynebacterium glutamicummannose enzyme II and analysis of the deduced protein sequence. FEMS Microbiol Lett. 1994 Jun. 1;119(1-2):137-45.
Wagner E, et al. Cloning and characterization of the scrA gene encoding the sucrose-specific Enzyme II of the phosphotransferase system fromStaphylococcus xylosus. Mol Gen Genet. 1993 Oct.;241(1-2):33-41.

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