Cortistatin: nucleic acids that encode these neuropeptides

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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536 2351, 4353201, 935 13, C12N 1516, C12N 510, C12N 1563, C12N 1585

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active

060748729

ABSTRACT:
The present invention relates generally to nucleic acids encoding a novel neuropeptide designated cortistatin. The cortistatin nucleic acids, proteins and polypeptides thereof along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.

REFERENCES:
patent: 5426099 (1995-06-01), Komisaruk et al.
de Lecea et al. Nature 381 (1996) 242-245.

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