Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Hormone or other secreted growth regulatory factor,...
Patent
1996-06-07
2000-03-21
Kemmerer, Elizabeth
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Hormone or other secreted growth regulatory factor,...
424562, 514 12, 514 13, 514 15, 514 17, 514 18, 514925, A61K 3806
Patent
active
060399562
ABSTRACT:
The invention includes a substantially pure preparation of a peptide having corticotropin release inhibiting factor (CRIF) activity comprising at least three contiguous amino acids contained within the amino acid sequence positioned between the fourth and fifth thyrotropin releasing hormone (TRH) sequence on a prepro-TRH protein. The CRIF peptide further comprises the fourth uncleaved TRH portion of prepro-TRH positioned at the amino terminus of CRIF. Compositions, methods of diagnosis and methods of treating CRIF related diseases are also included in the invention.
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Aird Fraser
McGivern Robert F.
Redei Eva
Rittenhouse Peter A.
Kemmerer Elizabeth
Pennsylvania, Trustees of the University of, The
Romeo David S.
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