Corticoid-containing preparation for topical application

Details Corticoid-containing preparation for topical application Corticoid-containing preparation for topical application

1988-10-17

1990-04-17

Lipovsky, Joseph A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514180, A61K 3156

Patent

active

049180657

ABSTRACT:
A corticoid-containing pharmaceutical preparation adapted for topical application, comprising 0.005-2% by weight of a corticoid having antiinflammatory activity, a fatty phase, an aqueous phase, an emulsifier, a preservative, and, optionally, a fragrant substance, or an additional hydrophilic or lipophilic cosmetically active ingredients, wherein the fatty phase, and the aqueous phase are present in the form of a dispersed mixture of an oil/water emulsifier and a preservative, and a water/oil emulsion containing a water/oil emulsifier, the particle size of the inner phase of the emulsions being 2-50 .mu.m.

REFERENCES:
patent: 4115313 (1978-09-01), Lyon et al.
patent: 4284630 (1981-08-01), Yu et al.
Die Emulsionen in der Hauttherapie, S. Hirzel Verlag Stuttgart, p. 223, 1951.
Brunegger et al., Sci. Pharm. 53, 1985, pp. 223-236.
"Vivoane" Brochure, pp. 3, and 6-13.
Test Report I, AT-2071/81.

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