Corticoid-17-alkyl-carbonates substituted in the 17-position, pr

Details Corticoid-17-alkyl-carbonates substituted in the 17-position, pr Corticoid-17-alkyl-carbonates substituted in the 17-position, pr

1993-02-08

1994-11-08

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514180, 514181, 552572, 552573, 552574, 552576, 552577, 552597, C07J 900

Patent

active

053627210

ABSTRACT:
The disclosed invention includes corticoid-17-alkylcarbonates substituted in the 17-position, a process for their preparation and pharmaceuticals containing them. These corticoid-17-alkylcarbonates have the following formula I ##STR1## where A is CHOH in any desired steric arrangement, C.dbd.O or CH.sub.2 ; Y is H, F, or Cl; Z is H, F or CH.sub.3 ; R(1) is O-acyl, carbonylalkyl, alkylsulfonate or arylsulfonate;

REFERENCES:
patent: 3621014 (1971-11-01), Stache et al.
patent: 4242334 (1980-12-01), Stache et al.
patent: 4377575 (1983-03-01), Stache et al.
Arzneim.-Forsch./Drug Res. 35 (I), No. 6 (1985) pp. 939-946, Vogel et al.--Prednicarbate.

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