Cortical steroid nitrogen mustard compositions and treatment the

Details Cortical steroid nitrogen mustard compositions and treatment the Cortical steroid nitrogen mustard compositions and treatment the

1973-03-13

1977-06-14

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3156

Patent

active

040297780

ABSTRACT:
New 21-esters of corticoid steroid hormones, the esters having an antitumor activity, are prepared by reacting a reactive derivative of the general formula ##STR1## wherein R.sup.1 can be hydrogen, lower alkyl, halogen, or lower alkoxy, X can be oxygen, sulphur, or a monovalent carbon-to-carbon bond, A can be alkylene, aminoalkylene, or lower-alkanoyl aminoalkylene, and A together with X also can be a monovalent carbon-to-carbon bond, with a corticoid steroid.

REFERENCES:
patent: 2983649 (1961-05-01), Ercoli
patent: 3073743 (1963-01-01), Spero
patent: 3083197 (1963-03-01), Brown et al.
patent: 3484436 (1969-12-01), Cross et al.
patent: 3649622 (1972-03-01), Epuran

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