Correction method for the distribution of quantity of light...

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

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C435S006120, C435S007100, C435S287200, C422S068100

Reexamination Certificate

active

07666663

ABSTRACT:
The present invention is characterized by the following points:In a biochip reader used for reading a measurement sample image by light beam irradiation, a correction method for the distribution of quantity of light which is devised to remove the influence of shading for the whole image and such a biochip reader can be realized by correcting non-uniformity in said quantity of light in light beam irradiation by dividing the quantities of light of pixels in a measured image obtained from the measurement of a measurement sample by a distribution of quantity of light in an image obtained from the measurement of a uniform fluorescent plate that presents a uniform fluorescent light distribution, the positions of pixels in the measured image being correspondent to those in the image obtained through the above uniform fluorescent plate measurement.

REFERENCES:
patent: 2003/0030797 (2003-02-01), Palladino et al.
patent: 2003/0105195 (2003-06-01), Holcomb et al.
patent: 2003-28799 (2003-01-01), None
patent: WO 01/55964 (2001-08-01), None
patent: WO 01/59503 (2001-08-01), None
patent: WO 03/000300 (2003-01-01), None
patent: 2004/101354 (2004-02-01), None
patent: WO 2004/023117 (2004-03-01), None
Y. Zhai et al. “Quantitative determination of the proportion of microtubule polymer present during the mitosis-interphase transition”, Journal of Cell Science 107, pp. 881-890 (1984).

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