Corpuscles of stannius protein, stanniocalcin

Details Corpuscles of stannius protein, stanniocalcin Corpuscles of stannius protein, stanniocalcin

1995-04-28

1999-11-30

Ulm, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530399, 530326, 530835, A61K 3817, A61K 3804, C07K 14435, C07K 14575

Patent

active

059943017

ABSTRACT:
The present invention relates to human Corpuscles of Stannius polypeptides and DNA (RNA) encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and antagonists against such polypeptides. Also provided are methods of using the polypeptide therapeutically for treating renal, bone and heart diseases and for using the antagonists for treating hypocalcemia and osteoporosis. Also provided is a diagnostic assay to detect mutations in the nucleic acid sequence encoding the polypeptide and for altered concentrations of the polypeptide in a sample derived from a host.

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